ЗНАЧЕНИЕ КИШЕЧНОЙ МИКРОБИОТЫ В РАЗВИТИИ ЗАБОЛЕВАНИЙ АУТИСТИЧЕСКОГО СПЕКТРА
Аннотация
Расстройства аутистического спектра (по англ. ASD или по русс. РАС) широко исследуются как одно из заболеваний нервной системы, связанных с кишечным микробиомом. Использование знаний о микробах помогает комплексно понять это заболевание. Интересно, что исследователи также привлекли внимание ротовой полости матери и вагинального микробиома как важного фактора этиопатологии расстройств аутистического спектра (РАС). Таким образом, в этом обзоре предпринята попытка обобщить знания о микробиоме и его связи с предполагаемой этиологией АСК и связанных с ним заболеваний. Также было проанализировано влияние пребиотиков, пробиотиков и трансплантации фекальных микробов на РАС. Среди них использование диеты и пробиотиков является наиболее перспективным и современным средством в связи с тем, что они не имеют побочных эффектов и их легко принимать. Текущие пробелы в знаниях и исследованиях требуют более масштабных и смелых исследований взаимосвязи между аутизмом и микробиомом.
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